Ontology-based Brucella vaccine literature indexing and systematic analysis of gene-vaccine association network

Type: 
Master's theses
Topics: 
Vaccinology
Countries: 
United States of America
Author(s): 
HUR, [Et. al]
Publication date: 
01/01/2011

Vaccine literature indexing is poorly performed in PubMed due to limited hierarchy of Medical Subject Headings (MeSH) annotation in the vaccine field. Vaccine Ontology (VO) is a community-based biomedical ontology that represents various vaccines and their relations. SciMiner is an in-house literature mining system that supports literature indexing and gene name tagging. We hypothesize that application of VO in SciMiner will aid vaccine literature indexing and mining of vaccine-gene interaction networks. As a test case, we have examined vaccines for Brucella, the causative agent of brucellosis in humans and animals. VO-SciMiner can be used to improve the efficiency for PubMed searching in the vaccine domain.

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Tags: 
Brucella vaccine terms, VO-SciMiner, Brucella gene, Gene-vaccine, vaccine literature,